Both penicillin and amoxycillin should be tested in antimicrobial surveillance for Streptococcus pneumoniae
نویسندگان
چکیده
منابع مشابه
Comparative in-vitro activities of amoxycillin and penicillin against Streptococcus pneumoniae isolates.
Sir, In a recent issue of this Journal, Verhaegen & Verbist reported on the in-vitro activities of 21 -lactams against penicillin-susceptible and -resistant isolates of Strepto coccus pneumoniae. The results of this investigation are surprising because they suggest that amoxycillin is less active than penicillin against these strains. We have recently determined the in-vitro susceptibilities of...
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Streptococcus pneumoniae is a major cause of pneumonia, meningitis, septicemia, acute otitis media, and other serious infections, severely affecting infants, young children, and the elderly. In the past, S. pneumoniae was uniformly susceptible to penicillin, which remained the drug of choice for serious infections. However, since the mid-1960s, resistance to penicillin, which was first reported...
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Heteroresistance to beta-lactam antibiotics has been mainly described for staphylococci, for which it complicates diagnostic procedures and therapeutic success. This study investigated whether heteroresistance to penicillin exists in Streptococcus pneumoniae. Population analysis profile (PAP) showed the presence of subpopulations with higher penicillin resistance in four of nine clinical pneumo...
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The activity of omadacycline and comparators when tested against a subset of Streptococcus pneumoniae from US and European regions of a 2014 global surveillance program (304 isolates) are reported. These MIC results were compared to those obtained when testing S. pneumoniae from 2010 surveillance (1,834 isolates). The omadacycline MIC50/90 for S. pneumoniae (2014) was 0.06/0.06μg/mL, similar to...
متن کاملAntibiotic combinations: should they be tested?
When antibiotic combinations are used to provide a broader spectrum of antimicrobial activity or in an attempt to prevent the emergence of resistant organisms, it is rarely necessary or practical to perform tests of drug interactions in vitro. In vitro testing of combinations may be useful when combinations are used in an attempt to attain synergistic interactions. In some cases, screening meth...
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ژورنال
عنوان ژورنال: Clinical Microbiology and Infection
سال: 2005
ISSN: 1198-743X
DOI: 10.1111/j.1469-0691.2005.01130.x